Drug interactions
Bacitracin + Foscarnet
Severity: Major
Bacitracin and Foscarnet: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Foscarnet commonly causes kidney injury, and systemic bacitracin is also nephrotoxic. Together they increase the risk of significant renal impairment.
What this interaction means in plain words
Bacitracin and Foscarnet can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin belongs to Miscellaneous; Foscarnet belongs to Anti Virals.
Why it happens
Additive nephrotoxicity.
What to do
Avoid systemic bacitracin and use an alternative where possible. If both are needed, hydrate well and monitor creatinine frequently, adjusting the foscarnet dose.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Other interactions of Bacitracin
- Bacitracin + Cidofovir Contraindicated
- Adefovir + Bacitracin Major
- Aldesleukin + Bacitracin Major
- Amikacin + Bacitracin Major
- Bacitracin + Carboplatin Major
- Bacitracin + Cisplatin Major
Frequently asked questions
Can I take Bacitracin with Foscarnet?
MediHelp rates the interaction as major. Bacitracin and Foscarnet can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Foscarnet commonly causes kidney injury, and systemic bacitracin is also nephrotoxic. Together they increase the risk of significant renal impairment.
How serious is the interaction between Bacitracin and Foscarnet?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic bacitracin and use an alternative where possible. If both are needed, hydrate well and monitor creatinine frequently, adjusting the foscarnet dose.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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