Drug interactions
Balsalazide + Meclofenamic acid
Severity: Minor
Balsalazide and Meclofenamic acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are acids that may compete for renal tubular secretion, but systemic exposure to balsalazide metabolites is low. NSAIDs may also worsen colitis in some patients and mesalamine products carry rare nephrotoxicity.
What this interaction means in plain words
Balsalazide and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Balsalazide belongs to Gastrointestinal Tract; Meclofenamic acid belongs to Musculoskeletal.
Why it happens
Possible competition for renal organic anion tubular secretion; also additive potential for renal effects.
What to do
Generally no change needed. Monitor renal function periodically and watch for worsening colitis symptoms with NSAID use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Meclofenamic acid
- Ketorolac intranasal + Meclofenamic acid Contraindicated
- Ketorolac + Meclofenamic acid Contraindicated
- Aceclofenac + Meclofenamic acid Major
- Acemetacin + Meclofenamic acid Major
- Alteplase + Meclofenamic acid Major
- Amiloride + Meclofenamic acid Major
Other interactions of Balsalazide
Frequently asked questions
Can I take Balsalazide with Meclofenamic acid?
MediHelp rates the interaction as minor. Balsalazide and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are acids that may compete for renal tubular secretion, but systemic exposure to balsalazide metabolites is low. NSAIDs may also worsen colitis in some patients and mesalamine products carry rare nephrotoxicity.
How serious is the interaction between Balsalazide and Meclofenamic acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Generally no change needed. Monitor renal function periodically and watch for worsening colitis symptoms with NSAID use.
What other medicines interact with Meclofenamic acid?
MediHelp also lists interactions of Meclofenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meclofenamic acid page.
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