Drug interactions
Balsalazide + Valganciclovir
Severity: Minor
Balsalazide and Valganciclovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mesalamine metabolites may compete with ganciclovir, the active form of valganciclovir, for renal tubular secretion. Ganciclovir exposure could rise slightly, and both drugs can affect renal function. The effect is likely small.
What this interaction means in plain words
Balsalazide and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Balsalazide belongs to Gastrointestinal Tract; Valganciclovir belongs to Anti Virals.
Why it happens
Competition for renal tubular anion secretion, with possible additive renal effects.
What to do
Monitor renal function and blood counts as already required for valganciclovir. Adjust the valganciclovir dose according to creatinine clearance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Balsalazide
Other interactions of Valganciclovir
Frequently asked questions
Can I take Balsalazide with Valganciclovir?
MediHelp rates the interaction as minor. Balsalazide and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mesalamine metabolites may compete with ganciclovir, the active form of valganciclovir, for renal tubular secretion. Ganciclovir exposure could rise slightly, and both drugs can affect renal function. The effect is likely small.
How serious is the interaction between Balsalazide and Valganciclovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and blood counts as already required for valganciclovir. Adjust the valganciclovir dose according to creatinine clearance.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
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