Drug interactions
Bazedoxifene / conjugated estrogens + Gentamicin
Severity: Minor
Bazedoxifene / conjugated estrogens and Gentamicin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic gentamicin is not established to reduce estrogen exposure, since the proposed mechanism of altered gut flora applies mainly to certain broad-spectrum oral antibiotics. A clinically meaningful effect on this menopausal hormone product is unlikely.
What this interaction means in plain words
Bazedoxifene / conjugated estrogens and Gentamicin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical reduction of enterohepatic estrogen recycling through gut flora changes; not established for parenteral gentamicin.
What to do
No specific action is needed beyond awareness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gentamicin
- Cidofovir + Gentamicin Contraindicated
- Adefovir + Gentamicin Major
- Amikacin + Gentamicin Major
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Major
- Amphotericin b deoxycholate + Gentamicin Major
- Amphotericin b + Gentamicin Major
Frequently asked questions
Can I take Bazedoxifene / conjugated estrogens with Gentamicin?
MediHelp rates the interaction as minor. Bazedoxifene / conjugated estrogens and Gentamicin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic gentamicin is not established to reduce estrogen exposure, since the proposed mechanism of altered gut flora applies mainly to certain broad-spectrum oral antibiotics. A clinically meaningful effect on this menopausal hormone product is unlikely.
How serious is the interaction between Bazedoxifene / conjugated estrogens and Gentamicin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond awareness.
What other medicines interact with Gentamicin?
MediHelp also lists interactions of Gentamicin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Gentamicin page.
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