Drug interactions
Bazedoxifene-conjugated estrogens + Ropinirole
Severity: Minor
Bazedoxifene-conjugated estrogens and Ropinirole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Estrogens have been reported to raise ropinirole concentrations, which may increase dopaminergic effects such as nausea, dizziness and somnolence. The effect is usually modest.
What this interaction means in plain words
Bazedoxifene-conjugated estrogens and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bazedoxifene-conjugated estrogens belongs to Endocrine; Ropinirole belongs to Central Nervous System.
Why it happens
Probable reduction of CYP1A2-mediated ropinirole clearance by estrogens.
What to do
Monitor for dopaminergic adverse effects and adjust the ropinirole dose when estrogen is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bazedoxifene-conjugated estrogens
- Anastrozole + Bazedoxifene-conjugated estrogens Contraindicated
- Bazedoxifene-conjugated estrogens + Ospemifene Contraindicated
- Antithrombin alfa + Bazedoxifene-conjugated estrogens Major
- Antithrombin iii + Bazedoxifene-conjugated estrogens Major
- Bazedoxifene-conjugated estrogens + Bemiparin Major
- Bazedoxifene-conjugated estrogens + Carbamazepine Major
Other interactions of Ropinirole
- Amisulpride + Ropinirole Contraindicated
- Chlorpromazine + Ropinirole Major
- Droperidol + Ropinirole Major
- Fluphenazine + Ropinirole Major
- Fluvoxamine + Ropinirole Major
- Haloperidol + Ropinirole Major
Frequently asked questions
Can I take Bazedoxifene-conjugated estrogens with Ropinirole?
MediHelp rates the interaction as minor. Bazedoxifene-conjugated estrogens and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Estrogens have been reported to raise ropinirole concentrations, which may increase dopaminergic effects such as nausea, dizziness and somnolence. The effect is usually modest.
How serious is the interaction between Bazedoxifene-conjugated estrogens and Ropinirole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for dopaminergic adverse effects and adjust the ropinirole dose when estrogen is started or stopped.
What other medicines interact with Bazedoxifene-conjugated estrogens?
MediHelp also lists interactions of Bazedoxifene-conjugated estrogens with, for example, Anastrozole, Ospemifene, Antithrombin alfa. The full list is on the Bazedoxifene-conjugated estrogens page.
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