Drug interactions
Bcg vaccine live + Gemifloxacin
Severity: Moderate
Bcg vaccine live and Gemifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Live BCG vaccine requires viable bacteria to elicit immunity, and systemic antibacterial therapy may blunt this response. The clinical impact with gemifloxacin is uncertain.
What this interaction means in plain words
Bcg vaccine live and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Antibacterial activity may suppress replication of the live attenuated vaccine organism.
What to do
Defer BCG vaccination until the antibiotic course is finished, or revaccinate if it was given during therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Frequently asked questions
Can I take Bcg vaccine live with Gemifloxacin?
MediHelp rates the interaction as moderate. Bcg vaccine live and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG vaccine requires viable bacteria to elicit immunity, and systemic antibacterial therapy may blunt this response. The clinical impact with gemifloxacin is uncertain.
How serious is the interaction between Bcg vaccine live and Gemifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer BCG vaccination until the antibiotic course is finished, or revaccinate if it was given during therapy.
What other medicines interact with Gemifloxacin?
MediHelp also lists interactions of Gemifloxacin with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Gemifloxacin page.
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