Drug interactions
Bcg vaccine live + Nitrofurantoin
Severity: Minor
Bcg vaccine live and Nitrofurantoin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nitrofurantoin is a urinary antibacterial with little systemic activity and no meaningful activity against mycobacteria. A clinically relevant effect on live BCG vaccine is not established.
What this interaction means in plain words
Bcg vaccine live and Nitrofurantoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism; nitrofurantoin reaches negligible systemic concentrations.
What to do
No special action is generally required; if concerned, schedule vaccination after the antibiotic course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nitrofurantoin
Frequently asked questions
Can I take Bcg vaccine live with Nitrofurantoin?
MediHelp rates the interaction as minor. Bcg vaccine live and Nitrofurantoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nitrofurantoin is a urinary antibacterial with little systemic activity and no meaningful activity against mycobacteria. A clinically relevant effect on live BCG vaccine is not established.
How serious is the interaction between Bcg vaccine live and Nitrofurantoin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No special action is generally required; if concerned, schedule vaccination after the antibiotic course.
What other medicines interact with Nitrofurantoin?
MediHelp also lists interactions of Nitrofurantoin with, for example, Pexidartinib, Pretomanid, Aluminum hydroxide. The full list is on the Nitrofurantoin page.
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