Drug reference
nitrofurantoin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Miscellaneous(Anti Bacterial))
Mechanism of action
Inactivates or alters bacterial ribosomal proteins and other macromolecules that may interfere with metabolism and cell-wall synthesis
Common side effects
- Arthralgia
- Anorexia
- Cough
- Chills
- Chest pains
Contraindications
- Renal failure (anuria, oliguria, or CrCl <60 mL/min) Pregnancy at term (38-42 weeks of gestation), during labor and delivery, or when onset of labor is imminent History of hepatic dysfunction/cholestatic jaundice associated with nitrofurantoin Neonates (<28 days) owing to possible hemolyti…
Known interactions (1)
- Methotrexate + nitrofurantoin Moderate
Related conditions
Frequently asked questions
What drug class is nitrofurantoin?
nitrofurantoin belongs to: Anti Bacterial.
How does nitrofurantoin work?
Inactivates or alters bacterial ribosomal proteins and other macromolecules that may interfere with metabolism and cell-wall synthesis
What are the common side effects of nitrofurantoin?
Arthralgia, Anorexia, Cough, Chills, Chest pains
Which drugs interact with nitrofurantoin?
Methotrexate
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