Drug interactions
Beclomethasone + Chlorothiazide
Severity: Minor
Beclomethasone and Chlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both thiazide diuretics and corticosteroids can lower serum potassium. With inhaled beclomethasone, systemic exposure is small, so clinically relevant hypokalemia is uncommon.
What this interaction means in plain words
Beclomethasone and Chlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Beclomethasone belongs to Respiratory; Chlorothiazide belongs to Cardiovascular.
Why it happens
Additive urinary potassium loss from thiazide distal tubular effects and corticosteroid mineralocorticoid activity.
What to do
Check serum potassium periodically, especially with high-dose inhaled steroid or other hypokalemic risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Beclomethasone
Other interactions of Chlorothiazide
Frequently asked questions
Can I take Beclomethasone with Chlorothiazide?
MediHelp rates the interaction as minor. Beclomethasone and Chlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both thiazide diuretics and corticosteroids can lower serum potassium. With inhaled beclomethasone, systemic exposure is small, so clinically relevant hypokalemia is uncommon.
How serious is the interaction between Beclomethasone and Chlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium periodically, especially with high-dose inhaled steroid or other hypokalemic risk factors.
What other medicines interact with Beclomethasone?
MediHelp also lists interactions of Beclomethasone with, for example, Corticorelin, Macimorelin, Sipuleucel-t. The full list is on the Beclomethasone page.
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