Drug interactions
Bedaquiline + Formoterol
Severity: Moderate
Bedaquiline and Formoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bedaquiline prolongs the QT interval, and formoterol can cause tachycardia, hypokalemia and QT prolongation. Together they may increase the risk of torsades de pointes, particularly with electrolyte disturbances or heart disease.
What this interaction means in plain words
Bedaquiline and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bedaquiline belongs to Anti Bacterial; Formoterol belongs to Respiratory.
Why it happens
Additive QT prolongation, with formoterol-induced hypokalemia potentially increasing arrhythmia risk.
What to do
Obtain baseline and periodic ECGs and keep potassium, magnesium and calcium within normal range. Review the need for formoterol or consider alternatives if QTc becomes markedly prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Bedaquiline
- Bedaquiline + Ziprasidone Contraindicated
- Alfuzosin + Bedaquiline Major
- Amiodarone + Bedaquiline Major
- Amisulpride + Bedaquiline Major
- Amitriptyline + Bedaquiline Major
- Amobarbital + Bedaquiline Major
Frequently asked questions
Can I take Bedaquiline with Formoterol?
MediHelp rates the interaction as moderate. Bedaquiline and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bedaquiline prolongs the QT interval, and formoterol can cause tachycardia, hypokalemia and QT prolongation. Together they may increase the risk of torsades de pointes, particularly with electrolyte disturbances or heart disease.
How serious is the interaction between Bedaquiline and Formoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain baseline and periodic ECGs and keep potassium, magnesium and calcium within normal range. Review the need for formoterol or consider alternatives if QTc becomes markedly prolonged.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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