Drug interactions
Benazepril + Ropinirole
Severity: Minor
Benazepril and Ropinirole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ropinirole is associated with orthostatic hypotension and syncope, which may be intensified by benazepril. The risk is greatest when treatment is started or the dose is increased.
What this interaction means in plain words
Benazepril and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Benazepril belongs to Cardiovascular; Ropinirole belongs to Central Nervous System.
Why it happens
Additive hypotensive effects of dopamine agonism-related autonomic effects and ACE inhibition.
What to do
Titrate ropinirole slowly, check orthostatic blood pressure, and counsel patients about dizziness on standing.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Other interactions of Ropinirole
- Amisulpride + Ropinirole Contraindicated
- Chlorpromazine + Ropinirole Major
- Droperidol + Ropinirole Major
- Fluphenazine + Ropinirole Major
- Fluvoxamine + Ropinirole Major
- Haloperidol + Ropinirole Major
Frequently asked questions
Can I take Benazepril with Ropinirole?
MediHelp rates the interaction as minor. Benazepril and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ropinirole is associated with orthostatic hypotension and syncope, which may be intensified by benazepril. The risk is greatest when treatment is started or the dose is increased.
How serious is the interaction between Benazepril and Ropinirole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate ropinirole slowly, check orthostatic blood pressure, and counsel patients about dizziness on standing.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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