Drug interactions
Bendroflumethiazide + Labetalol
Severity: Minor
Bendroflumethiazide and Labetalol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazide diuretics are commonly combined with beta-blockers for hypertension and the effects are additive. Thiazides can worsen glucose tolerance and cause hypokalemia, and beta-blockers may mask hypoglycemia symptoms in diabetic patients.
What this interaction means in plain words
Bendroflumethiazide and Labetalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive effects; thiazide-induced metabolic changes.
What to do
Monitor blood pressure, potassium and glucose, especially in diabetic patients. No dose change is usually needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Labetalol
- Amifostine + Labetalol Major
- Amiodarone + Labetalol Major
- Atenolol-chlorthalidone + Labetalol Major
- Atenolol + Labetalol Major
- Betaxolol + Labetalol Major
- Bisoprolol + Labetalol Major
Frequently asked questions
Can I take Bendroflumethiazide with Labetalol?
MediHelp rates the interaction as minor. Bendroflumethiazide and Labetalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazide diuretics are commonly combined with beta-blockers for hypertension and the effects are additive. Thiazides can worsen glucose tolerance and cause hypokalemia, and beta-blockers may mask hypoglycemia symptoms in diabetic patients.
How serious is the interaction between Bendroflumethiazide and Labetalol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, potassium and glucose, especially in diabetic patients. No dose change is usually needed.
What other medicines interact with Labetalol?
MediHelp also lists interactions of Labetalol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Labetalol page.
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