Drug interactions
Bendroflumethiazide + Metoprolol
Severity: Minor
Bendroflumethiazide and Metoprolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The combination is commonly used for hypertension and gives additive blood pressure lowering. Thiazides can cause hypokalemia, hyperglycemia and hyperuricemia, and beta-blockers can mask hypoglycemia and slightly worsen glucose control.
What this interaction means in plain words
Bendroflumethiazide and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive effects through different mechanisms, with thiazide-related metabolic changes.
What to do
Monitor blood pressure, serum potassium and glucose, especially in diabetic patients. Correct hypokalemia if it develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metoprolol
- Metoprolol + Thioridazine Contraindicated
- Amifostine + Metoprolol Major
- Amiodarone + Metoprolol Major
- Atenolol-chlorthalidone + Metoprolol Major
- Atenolol + Metoprolol Major
- Betaxolol + Metoprolol Major
Frequently asked questions
Can I take Bendroflumethiazide with Metoprolol?
MediHelp rates the interaction as minor. Bendroflumethiazide and Metoprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The combination is commonly used for hypertension and gives additive blood pressure lowering. Thiazides can cause hypokalemia, hyperglycemia and hyperuricemia, and beta-blockers can mask hypoglycemia and slightly worsen glucose control.
How serious is the interaction between Bendroflumethiazide and Metoprolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, serum potassium and glucose, especially in diabetic patients. Correct hypokalemia if it develops.
What other medicines interact with Metoprolol?
MediHelp also lists interactions of Metoprolol with, for example, Thioridazine, Amifostine, Amiodarone. The full list is on the Metoprolol page.
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