Drug interactions
Benperidol + Nabilone
Severity: Moderate
Benperidol and Nabilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Benperidol is a potent antipsychotic with sedative properties, and nabilone adds sedation, dizziness and hypotension. Nabilone may also cause psychiatric effects that could complicate treatment of psychosis.
What this interaction means in plain words
Benperidol and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive central nervous system depression and hypotensive effects.
What to do
Monitor sedation, blood pressure and mental status; avoid nabilone in patients with active psychosis if possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabilone
Frequently asked questions
Can I take Benperidol with Nabilone?
MediHelp rates the interaction as moderate. Benperidol and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Benperidol is a potent antipsychotic with sedative properties, and nabilone adds sedation, dizziness and hypotension. Nabilone may also cause psychiatric effects that could complicate treatment of psychosis.
How serious is the interaction between Benperidol and Nabilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation, blood pressure and mental status; avoid nabilone in patients with active psychosis if possible.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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