Drug interactions
Benzphetamine + Nabilone
Severity: Moderate
Benzphetamine and Nabilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Benzphetamine is a sympathomimetic anorectic, and both it and nabilone can raise heart rate. Benzphetamine does not reliably counter nabilone sedation, and the stimulant can worsen anxiety or agitation caused by cannabinoids.
What this interaction means in plain words
Benzphetamine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive tachycardic effects and opposing central effects; no reliable sedation antagonism.
What to do
Monitor heart rate, blood pressure and mental status; avoid in patients with significant cardiovascular disease or anxiety.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabilone
Frequently asked questions
Can I take Benzphetamine with Nabilone?
MediHelp rates the interaction as moderate. Benzphetamine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Benzphetamine is a sympathomimetic anorectic, and both it and nabilone can raise heart rate. Benzphetamine does not reliably counter nabilone sedation, and the stimulant can worsen anxiety or agitation caused by cannabinoids.
How serious is the interaction between Benzphetamine and Nabilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and mental status; avoid in patients with significant cardiovascular disease or anxiety.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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