Drug interactions
Berotralstat + Ciprofloxacin
Severity: Minor
Berotralstat and Ciprofloxacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Berotralstat inhibits P-glycoprotein and may modestly raise ciprofloxacin exposure. Clinical consequences are probably small at usual doses.
What this interaction means in plain words
Berotralstat and Ciprofloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Berotralstat belongs to Miscellaneous; Ciprofloxacin belongs to Anti Bacterial.
Why it happens
P-glycoprotein inhibition by berotralstat reduces ciprofloxacin efflux.
What to do
No dose adjustment is usually needed. Monitor for ciprofloxacin adverse effects such as GI upset, CNS effects and tendon pain.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Other interactions of Berotralstat
- Berotralstat + Ergotamine Major
- Berotralstat + Nilotinib Major
- Berotralstat + Pimozide Major
- Berotralstat + Quinidine Major
- Berotralstat + Quinine Major
- Berotralstat + Tacrolimus Major
Frequently asked questions
Can I take Berotralstat with Ciprofloxacin?
MediHelp rates the interaction as minor. Berotralstat and Ciprofloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Berotralstat inhibits P-glycoprotein and may modestly raise ciprofloxacin exposure. Clinical consequences are probably small at usual doses.
How serious is the interaction between Berotralstat and Ciprofloxacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed. Monitor for ciprofloxacin adverse effects such as GI upset, CNS effects and tendon pain.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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