Drug interactions
Betaxolol + Lasmiditan
Severity: Moderate
Betaxolol and Lasmiditan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan can lower heart rate, and in a study with a beta-blocker the heart rate fell further than with the beta-blocker alone. The effect is additive and may matter in patients with bradycardia or conduction disease.
What this interaction means in plain words
Betaxolol and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Betaxolol belongs to Cardiovascular; Lasmiditan belongs to Central Nervous System.
Why it happens
Additive heart rate lowering through pharmacodynamic synergism.
What to do
Monitor heart rate and symptoms of bradycardia, such as dizziness or syncope, after lasmiditan doses. Use extra care in patients with baseline bradycardia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Betaxolol with Lasmiditan?
MediHelp rates the interaction as moderate. Betaxolol and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan can lower heart rate, and in a study with a beta-blocker the heart rate fell further than with the beta-blocker alone. The effect is additive and may matter in patients with bradycardia or conduction disease.
How serious is the interaction between Betaxolol and Lasmiditan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and symptoms of bradycardia, such as dizziness or syncope, after lasmiditan doses. Use extra care in patients with baseline bradycardia.
What other medicines interact with Betaxolol?
MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.
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