Drug interactions
Betaxolol + Mirabegron
Severity: Minor
Betaxolol and Mirabegron: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol is partly metabolized by CYP2D6, so mirabegron may modestly raise its levels. This could enhance bradycardia or hypotension, though betaxolol has other clearance pathways.
What this interaction means in plain words
Betaxolol and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Betaxolol belongs to Cardiovascular; Mirabegron belongs to Genitourinary.
Why it happens
Moderate CYP2D6 inhibition by mirabegron.
What to do
Monitor heart rate and blood pressure when starting or stopping mirabegron.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mirabegron
- Digoxin + Mirabegron Major
- Flecainide + Mirabegron Major
- Mirabegron + Propafenone Major
- Mirabegron + Thioridazine Major
- Amitriptyline + Mirabegron Moderate
- Amoxapine + Mirabegron Moderate
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Mirabegron?
MediHelp rates the interaction as minor. Betaxolol and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Betaxolol is partly metabolized by CYP2D6, so mirabegron may modestly raise its levels. This could enhance bradycardia or hypotension, though betaxolol has other clearance pathways.
How serious is the interaction between Betaxolol and Mirabegron?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when starting or stopping mirabegron.
What other medicines interact with Mirabegron?
MediHelp also lists interactions of Mirabegron with, for example, Digoxin, Flecainide, Propafenone. The full list is on the Mirabegron page.
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