Drug interactions
Bevacizumab + Dengue vaccine
Severity: Moderate
Bevacizumab and Dengue vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The dengue vaccine is live attenuated, and patients receiving cancer therapy may mount a weaker response. Bevacizumab itself is not strongly immunosuppressive, so the interaction is mainly relevant when it is combined with chemotherapy.
What this interaction means in plain words
Bevacizumab and Dengue vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Concurrent antineoplastic therapy may impair immune response and increase risk with a live vaccine; bevacizumab's own contribution is unclear.
What to do
Avoid live vaccines in patients on active chemotherapy-containing regimens; schedule vaccination before treatment or after immune recovery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bevacizumab
- Bevacizumab + Sunitinib Major
- Bevacizumab + Daunorubicin Moderate
- Bevacizumab + Doxorubicin Moderate
- Bevacizumab + Doxorubicin liposomal Moderate
- Bevacizumab + Efgartigimod / hyaluronidase sc Moderate
- Bevacizumab + Efgartigimod alfa Moderate
Frequently asked questions
Can I take Bevacizumab with Dengue vaccine?
MediHelp rates the interaction as moderate. Bevacizumab and Dengue vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The dengue vaccine is live attenuated, and patients receiving cancer therapy may mount a weaker response. Bevacizumab itself is not strongly immunosuppressive, so the interaction is mainly relevant when it is combined with chemotherapy.
How serious is the interaction between Bevacizumab and Dengue vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines in patients on active chemotherapy-containing regimens; schedule vaccination before treatment or after immune recovery.
What other medicines interact with Bevacizumab?
MediHelp also lists interactions of Bevacizumab with, for example, Sunitinib, Daunorubicin, Doxorubicin. The full list is on the Bevacizumab page.
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