Drug interactions
Bevacizumab + Doxorubicin liposomal
Severity: Moderate
Bevacizumab and Doxorubicin liposomal: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents have been associated with cardiac dysfunction, and bevacizumab can cause hypertension and heart failure. Together the risk of cardiomyopathy may be increased.
What this interaction means in plain words
Bevacizumab and Doxorubicin liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive cardiotoxicity from anthracycline myocardial injury and bevacizumab-related hypertension and cardiac dysfunction.
What to do
Assess left ventricular ejection fraction before and during treatment and monitor blood pressure; stop or modify therapy if heart failure develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bevacizumab
- Bevacizumab + Sunitinib Major
- Bevacizumab + Daunorubicin Moderate
- Bevacizumab + Dengue vaccine Moderate
- Bevacizumab + Doxorubicin Moderate
- Bevacizumab + Efgartigimod / hyaluronidase sc Moderate
- Bevacizumab + Efgartigimod alfa Moderate
Frequently asked questions
Can I take Bevacizumab with Doxorubicin liposomal?
MediHelp rates the interaction as moderate. Bevacizumab and Doxorubicin liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents have been associated with cardiac dysfunction, and bevacizumab can cause hypertension and heart failure. Together the risk of cardiomyopathy may be increased.
How serious is the interaction between Bevacizumab and Doxorubicin liposomal?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess left ventricular ejection fraction before and during treatment and monitor blood pressure; stop or modify therapy if heart failure develops.
What other medicines interact with Bevacizumab?
MediHelp also lists interactions of Bevacizumab with, for example, Sunitinib, Daunorubicin, Dengue vaccine. The full list is on the Bevacizumab page.
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