Drug interactions
Bicalutamide + Flotufolastat f
Severity: Minor
Bicalutamide and Flotufolastat f: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgen receptor antagonists can change PSMA expression and tracer uptake in prostate cancer, which may affect interpretation of flotufolastat F 18 PET. The effect on scan performance has not been established.
What this interaction means in plain words
Bicalutamide and Flotufolastat f have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Androgen pathway blockade may alter PSMA expression and tracer uptake in prostate tumors.
What to do
Interpret PET results in light of ongoing androgen blockade and discuss with the nuclear medicine physician; do not stop therapy solely for imaging without oncology input.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bicalutamide
- Bicalutamide + Lomitapide Major
- Aminolevulinic acid + Bicalutamide Moderate
- Bicalutamide + Eliglustat Moderate
- Bicalutamide + Flibanserin Moderate
- Bicalutamide + Ivosidenib Moderate
- Bicalutamide + Lonafarnib Moderate
Frequently asked questions
Can I take Bicalutamide with Flotufolastat f?
MediHelp rates the interaction as minor. Bicalutamide and Flotufolastat f have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgen receptor antagonists can change PSMA expression and tracer uptake in prostate cancer, which may affect interpretation of flotufolastat F 18 PET. The effect on scan performance has not been established.
How serious is the interaction between Bicalutamide and Flotufolastat f?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Interpret PET results in light of ongoing androgen blockade and discuss with the nuclear medicine physician; do not stop therapy solely for imaging without oncology input.
What other medicines interact with Bicalutamide?
MediHelp also lists interactions of Bicalutamide with, for example, Lomitapide, Aminolevulinic acid, Eliglustat. The full list is on the Bicalutamide page.
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