Drug interactions
Bicalutamide + Gallium ga 68 psma-11
Severity: Minor
Bicalutamide and Gallium ga 68 psma-11: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgen pathway blockade can alter PSMA expression in prostate cancer cells, which may change tracer uptake and affect image interpretation. The magnitude and direction of the effect with bicalutamide are not well established.
What this interaction means in plain words
Bicalutamide and Gallium ga 68 psma-11 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Androgen receptor blockade may modulate PSMA expression and thus tracer uptake; the mechanism is not firmly established.
What to do
Inform the nuclear medicine physician of current antiandrogen therapy and interpret the scan in light of treatment timing.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bicalutamide
- Bicalutamide + Lomitapide Major
- Aminolevulinic acid + Bicalutamide Moderate
- Bicalutamide + Eliglustat Moderate
- Bicalutamide + Flibanserin Moderate
- Bicalutamide + Ivosidenib Moderate
- Bicalutamide + Lonafarnib Moderate
Frequently asked questions
Can I take Bicalutamide with Gallium ga 68 psma-11?
MediHelp rates the interaction as minor. Bicalutamide and Gallium ga 68 psma-11 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgen pathway blockade can alter PSMA expression in prostate cancer cells, which may change tracer uptake and affect image interpretation. The magnitude and direction of the effect with bicalutamide are not well established.
How serious is the interaction between Bicalutamide and Gallium ga 68 psma-11?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Inform the nuclear medicine physician of current antiandrogen therapy and interpret the scan in light of treatment timing.
What other medicines interact with Bicalutamide?
MediHelp also lists interactions of Bicalutamide with, for example, Lomitapide, Aminolevulinic acid, Eliglustat. The full list is on the Bicalutamide page.
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