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Drug interactions

Bicalutamide + Methyl aminolevulinate

Severity: Minor

Bicalutamide and Methyl aminolevulinate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Bicalutamide can cause photosensitivity, and methyl aminolevulinate is a topical photodynamic therapy agent that sensitizes treated skin to light. Combined, skin reactions to light exposure could theoretically be heightened, although topical absorption is minimal.

What this interaction means in plain words

Bicalutamide and Methyl aminolevulinate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Additive photosensitizing effects, largely theoretical given limited systemic exposure to the topical agent.

What to do

Advise strict sun and light protection of treated areas during and after photodynamic therapy and report unusual skin reactions.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Bicalutamide with Methyl aminolevulinate?

MediHelp rates the interaction as minor. Bicalutamide and Methyl aminolevulinate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bicalutamide can cause photosensitivity, and methyl aminolevulinate is a topical photodynamic therapy agent that sensitizes treated skin to light. Combined, skin reactions to light exposure could theoretically be heightened, although topical absorption is minimal.

How serious is the interaction between Bicalutamide and Methyl aminolevulinate?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise strict sun and light protection of treated areas during and after photodynamic therapy and report unusual skin reactions.

What other medicines interact with Bicalutamide?

MediHelp also lists interactions of Bicalutamide with, for example, Lomitapide, Aminolevulinic acid, Eliglustat. The full list is on the Bicalutamide page.

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