Drug interactions
Biotin + Streptomycin
Severity: Minor
Biotin and Streptomycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral streptomycin is poorly absorbed and can alter gut flora, which theoretically lowers bacterial biotin synthesis. Streptomycin is usually given by injection, and biotin comes mainly from the diet, so a clinically meaningful deficiency is very unlikely.
What this interaction means in plain words
Biotin and Streptomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Biotin belongs to Gastrointestinal Tract; Streptomycin belongs to Anti Bacterial.
Why it happens
Theoretical suppression of biotin-producing intestinal bacteria; not an established effect with injected streptomycin.
What to do
No action is required for typical use. Consider biotin status only with prolonged oral antibiotic therapy and poor dietary intake.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Streptomycin
Other interactions of Biotin
- Biotin + Levothyroxine Moderate
- Azithromycin + Biotin Minor
- Biotin + Carbamazepine Minor
- Biotin + Cefalexin Minor
- Biotin + Erythromycin base Minor
- Biotin + Erythromycin ethylsuccinate Minor
Frequently asked questions
Can I take Biotin with Streptomycin?
MediHelp rates the interaction as minor. Biotin and Streptomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral streptomycin is poorly absorbed and can alter gut flora, which theoretically lowers bacterial biotin synthesis. Streptomycin is usually given by injection, and biotin comes mainly from the diet, so a clinically meaningful deficiency is very unlikely.
How serious is the interaction between Biotin and Streptomycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is required for typical use. Consider biotin status only with prolonged oral antibiotic therapy and poor dietary intake.
What other medicines interact with Streptomycin?
MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Adefovir, Amikacin. The full list is on the Streptomycin page.
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