Drug interactions
Biotin + Tobramycin
Severity: Minor
Biotin and Tobramycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral tobramycin is poorly absorbed and may alter gut flora that contribute to biotin supply. Any reduction in biotin status is theoretical and unlikely to matter clinically.
What this interaction means in plain words
Biotin and Tobramycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Biotin belongs to Gastrointestinal Tract; Tobramycin belongs to Anti Bacterial.
Why it happens
Oral aminoglycoside may suppress biotin-synthesizing intestinal bacteria; this is theoretical.
What to do
No action is needed for short courses; consider biotin status only with prolonged oral aminoglycoside use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tobramycin
- Cidofovir + Tobramycin Contraindicated
- Adefovir + Tobramycin Major
- Amikacin + Tobramycin Major
- Amphotericin b deoxycholate + Tobramycin Major
- Amphotericin b + Tobramycin Major
- Atracurium + Tobramycin Major
Other interactions of Biotin
- Biotin + Levothyroxine Moderate
- Azithromycin + Biotin Minor
- Biotin + Carbamazepine Minor
- Biotin + Cefalexin Minor
- Biotin + Erythromycin base Minor
- Biotin + Erythromycin ethylsuccinate Minor
Frequently asked questions
Can I take Biotin with Tobramycin?
MediHelp rates the interaction as minor. Biotin and Tobramycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral tobramycin is poorly absorbed and may alter gut flora that contribute to biotin supply. Any reduction in biotin status is theoretical and unlikely to matter clinically.
How serious is the interaction between Biotin and Tobramycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for short courses; consider biotin status only with prolonged oral aminoglycoside use.
What other medicines interact with Tobramycin?
MediHelp also lists interactions of Tobramycin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Tobramycin page.
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