Drug interactions
Bisoprolol + Glucagon
Severity: Minor
Bisoprolol and Glucagon: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon increases heart rate and contractility independent of beta receptors and is used to treat beta-blocker overdose. In patients on bisoprolol it may transiently raise pulse and blood pressure, offsetting beta-blocker effects.
What this interaction means in plain words
Bisoprolol and Glucagon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bisoprolol belongs to Cardiovascular; Glucagon belongs to Endocrine.
Why it happens
Glucagon receptor-mediated increase in cyclic AMP bypasses blocked beta-adrenergic receptors.
What to do
No action is typically needed at routine doses; monitor heart rate and blood pressure when glucagon is used therapeutically.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bisoprolol
Other interactions of Glucagon
- Atropine + Glucagon Moderate
- Benztropine + Glucagon Moderate
- Dicyclomine + Glucagon Moderate
- Diphenoxylate-atropine + Glucagon Moderate
- Glucagon + Glycopyrronium Moderate
- Glucagon + Hyoscyamine Moderate
Frequently asked questions
Can I take Bisoprolol with Glucagon?
MediHelp rates the interaction as minor. Bisoprolol and Glucagon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon increases heart rate and contractility independent of beta receptors and is used to treat beta-blocker overdose. In patients on bisoprolol it may transiently raise pulse and blood pressure, offsetting beta-blocker effects.
How serious is the interaction between Bisoprolol and Glucagon?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is typically needed at routine doses; monitor heart rate and blood pressure when glucagon is used therapeutically.
What other medicines interact with Bisoprolol?
MediHelp also lists interactions of Bisoprolol with, for example, Aldesleukin, Amifostine, Amiodarone. The full list is on the Bisoprolol page.
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