Drug interactions
Dicyclomine + Glucagon
Severity: Moderate
Dicyclomine and Glucagon: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon inhibits gastrointestinal motility, and anticholinergics like dicyclomine do the same. Together they may increase gastrointestinal adverse effects such as ileus, constipation or distension. The risk is mainly relevant with diagnostic glucagon use.
What this interaction means in plain words
Dicyclomine and Glucagon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dicyclomine belongs to Respiratory; Glucagon belongs to Endocrine.
Why it happens
Additive inhibition of gastrointestinal motility through anticholinergic and glucagon effects.
What to do
Hold dicyclomine before diagnostic glucagon use unless needed. Monitor for abdominal distension, constipation and reduced bowel sounds.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dicyclomine
- Clozapine + Dicyclomine Major
- Dicyclomine + Henbane Major
- Dicyclomine + Imipramine Major
- Dicyclomine + Pramlintide Major
- Abobotulinumtoxina + Dicyclomine Moderate
- Aclidinium + Dicyclomine Moderate
Other interactions of Glucagon
- Atropine + Glucagon Moderate
- Benztropine + Glucagon Moderate
- Diphenoxylate-atropine + Glucagon Moderate
- Glucagon + Glycopyrrolate Moderate
- Glucagon + Glycopyrronium Moderate
- Glucagon + Hyoscyamine Moderate
Frequently asked questions
Can I take Dicyclomine with Glucagon?
MediHelp rates the interaction as moderate. Dicyclomine and Glucagon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glucagon inhibits gastrointestinal motility, and anticholinergics like dicyclomine do the same. Together they may increase gastrointestinal adverse effects such as ileus, constipation or distension. The risk is mainly relevant with diagnostic glucagon use.
How serious is the interaction between Dicyclomine and Glucagon?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Hold dicyclomine before diagnostic glucagon use unless needed. Monitor for abdominal distension, constipation and reduced bowel sounds.
What other medicines interact with Dicyclomine?
MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.
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