Drug interactions
Atropine + Glucagon
Severity: Moderate
Atropine and Glucagon: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon used as a diagnostic aid inhibits gastrointestinal motility, and anticholinergics such as atropine add to this effect. Together they may increase GI adverse effects such as ileus, constipation and abdominal distension.
What this interaction means in plain words
Atropine and Glucagon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Glucagon belongs to Endocrine.
Why it happens
Additive inhibition of gastrointestinal motility through pharmacodynamic effects.
What to do
Avoid anticholinergics when glucagon is used as a diagnostic aid for GI imaging. When glucagon is used for hypoglycemia, treat as needed and monitor for GI symptoms.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Glucagon
- Benztropine + Glucagon Moderate
- Dicyclomine + Glucagon Moderate
- Diphenoxylate-atropine + Glucagon Moderate
- Glucagon + Glycopyrrolate Moderate
- Glucagon + Glycopyrronium Moderate
- Glucagon + Hyoscyamine Moderate
Other interactions of Atropine
- Atropine + Eluxadoline Major
- Atropine + Henbane Major
- Atropine + Pramlintide Major
- Abobotulinumtoxina + Atropine Moderate
- Aclidinium + Atropine Moderate
- Amantadine + Atropine Moderate
Frequently asked questions
Can I take Atropine with Glucagon?
MediHelp rates the interaction as moderate. Atropine and Glucagon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glucagon used as a diagnostic aid inhibits gastrointestinal motility, and anticholinergics such as atropine add to this effect. Together they may increase GI adverse effects such as ileus, constipation and abdominal distension.
How serious is the interaction between Atropine and Glucagon?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid anticholinergics when glucagon is used as a diagnostic aid for GI imaging. When glucagon is used for hypoglycemia, treat as needed and monitor for GI symptoms.
What other medicines interact with Glucagon?
MediHelp also lists interactions of Glucagon with, for example, Benztropine, Dicyclomine, Diphenoxylate-atropine. The full list is on the Glucagon page.
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