Drug interactions
Bisoprolol + Lasmiditan
Severity: Moderate
Bisoprolol and Lasmiditan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan can lower heart rate. Combining it with a beta-blocker may produce a further, additive reduction in heart rate.
What this interaction means in plain words
Bisoprolol and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bisoprolol belongs to Cardiovascular; Lasmiditan belongs to Central Nervous System.
Why it happens
Additive heart rate lowering, with beta-1 blockade added to the bradycardic effect of lasmiditan.
What to do
Monitor heart rate and symptoms of bradycardia after lasmiditan dosing. Take care in patients with a low baseline heart rate or conduction disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bisoprolol
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Bisoprolol with Lasmiditan?
MediHelp rates the interaction as moderate. Bisoprolol and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan can lower heart rate. Combining it with a beta-blocker may produce a further, additive reduction in heart rate.
How serious is the interaction between Bisoprolol and Lasmiditan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and symptoms of bradycardia after lasmiditan dosing. Take care in patients with a low baseline heart rate or conduction disease.
What other medicines interact with Bisoprolol?
MediHelp also lists interactions of Bisoprolol with, for example, Aldesleukin, Amifostine, Amiodarone. The full list is on the Bisoprolol page.
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