Drug interactions
Bosutinib + Propranolol
Severity: Minor
Bosutinib and Propranolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propranolol may weakly inhibit P-glycoprotein, possibly increasing bosutinib exposure. The effect is likely minor.
What this interaction means in plain words
Bosutinib and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bosutinib belongs to Oncology; Propranolol belongs to Cardiovascular.
Why it happens
Possible P-glycoprotein inhibition reduces bosutinib efflux.
What to do
Monitor for bosutinib gastrointestinal and hepatic adverse effects. No routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Propranolol
- Propranolol + Thioridazine Contraindicated
- Acebutolol + Propranolol Major
- Adrenaline-articaine + Propranolol Major
- Amifostine + Propranolol Major
- Amiodarone + Propranolol Major
- Arformoterol + Propranolol Major
Other interactions of Bosutinib
- Amiodarone + Bosutinib Major
- Apalutamide + Bosutinib Major
- Aprepitant + Bosutinib Major
- Bosentan + Bosutinib Major
- Bosutinib + Carbamazepine Major
- Bosutinib + Chlorpromazine Major
Frequently asked questions
Can I take Bosutinib with Propranolol?
MediHelp rates the interaction as minor. Bosutinib and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Propranolol may weakly inhibit P-glycoprotein, possibly increasing bosutinib exposure. The effect is likely minor.
How serious is the interaction between Bosutinib and Propranolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bosutinib gastrointestinal and hepatic adverse effects. No routine dose change is needed.
What other medicines interact with Propranolol?
MediHelp also lists interactions of Propranolol with, for example, Thioridazine, Acebutolol, Adrenaline-articaine. The full list is on the Propranolol page.
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