Drug interactions
Bremelanotide + Buprenorphine
Severity: Minor
Bremelanotide and Buprenorphine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bremelanotide may slow gastric emptying, which could delay absorption of oral drugs. For buprenorphine, which is usually given sublingually, transdermally or by injection, the effect is likely to be negligible.
What this interaction means in plain words
Bremelanotide and Buprenorphine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bremelanotide belongs to Genitourinary; Buprenorphine belongs to Musculoskeletal.
Why it happens
Delayed gastric emptying with possible reduced oral absorption.
What to do
No routine action needed for non-oral buprenorphine. Monitor for efficacy if an oral formulation is swallowed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Buprenorphine
- Alvimopan + Buprenorphine Contraindicated
- Buprenorphine + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Buprenorphine + Olanzapine / samidorphan Contraindicated
- Buprenorphine + Phenelzine Contraindicated
- Buprenorphine + Pimozide Contraindicated
- Buprenorphine + Thioridazine Contraindicated
Other interactions of Bremelanotide
- Bremelanotide + Bupropion-naltrexone Moderate
- Bremelanotide + Cyclosporin Moderate
- Bremelanotide + Digoxin Moderate
- Bremelanotide + Disopyramide Moderate
- Bremelanotide + Naltrexone Moderate
- Bremelanotide + Procainamide Moderate
Frequently asked questions
Can I take Bremelanotide with Buprenorphine?
MediHelp rates the interaction as minor. Bremelanotide and Buprenorphine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bremelanotide may slow gastric emptying, which could delay absorption of oral drugs. For buprenorphine, which is usually given sublingually, transdermally or by injection, the effect is likely to be negligible.
How serious is the interaction between Bremelanotide and Buprenorphine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action needed for non-oral buprenorphine. Monitor for efficacy if an oral formulation is swallowed.
What other medicines interact with Buprenorphine?
MediHelp also lists interactions of Buprenorphine with, for example, Alvimopan, Calcium / magnesium / potassium / sodium oxybates, Olanzapine / samidorphan. The full list is on the Buprenorphine page.
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