Drug interactions
Brentuximab + Ublituximab
Severity: Moderate
Brentuximab and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can impair host defenses, brentuximab through myelosuppression and ublituximab through B-cell depletion. Together they may raise the risk of infections, including opportunistic infections.
What this interaction means in plain words
Brentuximab and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brentuximab belongs to Oncology; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunosuppression from cytotoxic myelosuppression and B-cell depletion.
What to do
Monitor blood counts and for signs of infection; consider antimicrobial prophylaxis as appropriate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brentuximab
- Bleomycin + Brentuximab Contraindicated
- Brentuximab + Dengue vaccine Major
- Brentuximab + Etrasimod Major
- Brentuximab + Idelalisib Major
- Brentuximab + Levoketoconazole Major
- Brentuximab + Nefazodone Major
Other interactions of Ublituximab
Frequently asked questions
Can I take Brentuximab with Ublituximab?
MediHelp rates the interaction as moderate. Brentuximab and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can impair host defenses, brentuximab through myelosuppression and ublituximab through B-cell depletion. Together they may raise the risk of infections, including opportunistic infections.
How serious is the interaction between Brentuximab and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and for signs of infection; consider antimicrobial prophylaxis as appropriate.
What other medicines interact with Brentuximab?
MediHelp also lists interactions of Brentuximab with, for example, Bleomycin, Dengue vaccine, Etrasimod. The full list is on the Brentuximab page.
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