Drug interactions
Brexpiprazole + Ethanol
Severity: Moderate
Brexpiprazole and Ethanol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alcohol enhances the sedative and psychomotor-impairing effects of brexpiprazole and can worsen dizziness and orthostatic hypotension. Alcohol may also worsen the psychiatric condition being treated.
What this interaction means in plain words
Brexpiprazole and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression from alcohol and antipsychotic sedative effects.
What to do
Advise patients to avoid or minimize alcohol while taking brexpiprazole. Counsel against driving after drinking.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Brexpiprazole and Ethanol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Brexpiprazole
Frequently asked questions
Can I take Brexpiprazole with Ethanol?
MediHelp rates the interaction as moderate. Brexpiprazole and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alcohol enhances the sedative and psychomotor-impairing effects of brexpiprazole and can worsen dizziness and orthostatic hypotension. Alcohol may also worsen the psychiatric condition being treated.
How serious is the interaction between Brexpiprazole and Ethanol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid or minimize alcohol while taking brexpiprazole. Counsel against driving after drinking.
What other medicines interact with Brexpiprazole?
MediHelp also lists interactions of Brexpiprazole with, for example, Alfentanil, Amisulpride, Apalutamide. The full list is on the Brexpiprazole page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
