Drug interactions
Brivaracetam + Dexbrompheniramine
Severity: Moderate
Brivaracetam and Dexbrompheniramine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexbrompheniramine is a sedating first-generation antihistamine. Combined with brivaracetam it may increase drowsiness and reduce alertness.
What this interaction means in plain words
Brivaracetam and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brivaracetam belongs to Central Nervous System; Dexbrompheniramine belongs to Respiratory.
Why it happens
Additive CNS depression from two sedating agents.
What to do
Counsel on drowsiness and avoid driving if affected. Use a non-sedating antihistamine where possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brivaracetam
Other interactions of Dexbrompheniramine
- Amisulpride + Dexbrompheniramine Moderate
- Asenapine + Dexbrompheniramine Moderate
- Brexpiprazole + Dexbrompheniramine Moderate
- Brimonidine + Dexbrompheniramine Moderate
- Cariprazine + Dexbrompheniramine Moderate
- Dexbrompheniramine + Esketamine Moderate
Frequently asked questions
Can I take Brivaracetam with Dexbrompheniramine?
MediHelp rates the interaction as moderate. Brivaracetam and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexbrompheniramine is a sedating first-generation antihistamine. Combined with brivaracetam it may increase drowsiness and reduce alertness.
How serious is the interaction between Brivaracetam and Dexbrompheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on drowsiness and avoid driving if affected. Use a non-sedating antihistamine where possible.
What other medicines interact with Brivaracetam?
MediHelp also lists interactions of Brivaracetam with, for example, Benzhydrocodone / acetaminophen, Sodium oxybate, Acetaminophen / phenyltoloxamine. The full list is on the Brivaracetam page.
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