Drug interactions
Brivaracetam + Meperidine
Severity: Minor
Brivaracetam and Meperidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brivaracetam can cause somnolence, dizziness and fatigue, and meperidine adds to these CNS effects. The combination may impair alertness and coordination.
What this interaction means in plain words
Brivaracetam and Meperidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brivaracetam belongs to Central Nervous System; Meperidine belongs to Musculoskeletal.
Why it happens
Additive CNS depressant effects; no significant pharmacokinetic interaction is expected.
What to do
Counsel patients about sedation and avoid driving until response is known. Reduce doses if drowsiness is troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Meperidine
- Alvimopan + Meperidine Contraindicated
- Isocarboxazid + Meperidine Contraindicated
- Meperidine + Methylene blue Contraindicated
- Meperidine + Olanzapine / samidorphan Contraindicated
- Meperidine + Phenelzine Contraindicated
- Meperidine + Procarbazine Contraindicated
Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Meperidine?
MediHelp rates the interaction as minor. Brivaracetam and Meperidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brivaracetam can cause somnolence, dizziness and fatigue, and meperidine adds to these CNS effects. The combination may impair alertness and coordination.
How serious is the interaction between Brivaracetam and Meperidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about sedation and avoid driving until response is known. Reduce doses if drowsiness is troublesome.
What other medicines interact with Meperidine?
MediHelp also lists interactions of Meperidine with, for example, Alvimopan, Isocarboxazid, Methylene blue. The full list is on the Meperidine page.
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