Drug interactions
Brivaracetam + Perphenazine
Severity: Minor
Brivaracetam and Perphenazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause somnolence, dizziness and fatigue, so combined use may add to CNS depression. The effect is generally modest and manageable.
What this interaction means in plain words
Brivaracetam and Perphenazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brivaracetam belongs to Central Nervous System; Perphenazine belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects.
What to do
Advise patients to watch for drowsiness and avoid driving until the response is known. Lower the dose of either drug if sedation becomes problematic.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Perphenazine
- Ibutilide + Perphenazine Contraindicated
- Perphenazine + Pimozide Contraindicated
- Perphenazine + Thioridazine Contraindicated
- Adagrasib + Perphenazine Major
- Alfentanil + Perphenazine Major
- Amiodarone + Perphenazine Major
Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Perphenazine?
MediHelp rates the interaction as minor. Brivaracetam and Perphenazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause somnolence, dizziness and fatigue, so combined use may add to CNS depression. The effect is generally modest and manageable.
How serious is the interaction between Brivaracetam and Perphenazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for drowsiness and avoid driving until the response is known. Lower the dose of either drug if sedation becomes problematic.
What other medicines interact with Perphenazine?
MediHelp also lists interactions of Perphenazine with, for example, Ibutilide, Pimozide, Thioridazine. The full list is on the Perphenazine page.
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