Drug interactions
Bromocriptine + Norepinephrine
Severity: Moderate
Bromocriptine and Norepinephrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bromocriptine has been associated with hypertension and arrhythmias, and norepinephrine is a potent vasopressor. Together they may produce additive pressor effects and rarely ventricular arrhythmias.
What this interaction means in plain words
Bromocriptine and Norepinephrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic sympathomimetic and vasoconstrictor effects.
What to do
Monitor blood pressure and heart rhythm continuously during norepinephrine infusion and titrate it to the lowest effective rate. Consider holding bromocriptine in acute critical illness.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bromocriptine
Frequently asked questions
Can I take Bromocriptine with Norepinephrine?
MediHelp rates the interaction as moderate. Bromocriptine and Norepinephrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bromocriptine has been associated with hypertension and arrhythmias, and norepinephrine is a potent vasopressor. Together they may produce additive pressor effects and rarely ventricular arrhythmias.
How serious is the interaction between Bromocriptine and Norepinephrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rhythm continuously during norepinephrine infusion and titrate it to the lowest effective rate. Consider holding bromocriptine in acute critical illness.
What other medicines interact with Bromocriptine?
MediHelp also lists interactions of Bromocriptine with, for example, Amisulpride, Atazanavir, Cobicistat. The full list is on the Bromocriptine page.
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