Drug interactions
Budesonide + Eliglustat
Severity: Minor
Budesonide and Eliglustat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eliglustat inhibits P-glycoprotein and may increase budesonide absorption and exposure. Higher exposure raises the risk of systemic corticosteroid effects.
What this interaction means in plain words
Budesonide and Eliglustat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Eliglustat belongs to Miscellaneous.
Why it happens
Eliglustat inhibits P-gp efflux, increasing budesonide absorption.
What to do
Monitor for signs of corticosteroid excess and reduce the budesonide dose if they appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Eliglustat
- Amiodarone + Eliglustat Contraindicated
- Clarithromycin + Eliglustat Contraindicated
- Dronedarone + Eliglustat Contraindicated
- Eliglustat + Itraconazole Contraindicated
- Eliglustat + Ketoconazole Contraindicated
- Eliglustat + Pimozide Contraindicated
Frequently asked questions
Can I take Budesonide with Eliglustat?
MediHelp rates the interaction as minor. Budesonide and Eliglustat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eliglustat inhibits P-glycoprotein and may increase budesonide absorption and exposure. Higher exposure raises the risk of systemic corticosteroid effects.
How serious is the interaction between Budesonide and Eliglustat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of corticosteroid excess and reduce the budesonide dose if they appear.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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