Drug interactions
Budesonide + Ethacrynic acid
Severity: Moderate
Budesonide and Ethacrynic acid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Loop diuretics such as ethacrynic acid and corticosteroids both increase potassium excretion, so combined use can cause additive hypokalemia. This matters most with systemically available budesonide, high diuretic doses, or concurrent digoxin or QT-prolonging drugs.
What this interaction means in plain words
Budesonide and Ethacrynic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide belongs to Respiratory; Ethacrynic acid belongs to Cardiovascular.
Why it happens
Additive renal potassium wasting from loop diuretic action and corticosteroid mineralocorticoid effects.
What to do
Monitor serum potassium and magnesium regularly and replace deficits. Adjust the diuretic or add potassium supplementation if hypokalemia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Budesonide and Ethacrynic acid, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Budesonide
Other interactions of Ethacrynic acid
Frequently asked questions
Can I take Budesonide with Ethacrynic acid?
MediHelp rates the interaction as moderate. Budesonide and Ethacrynic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Loop diuretics such as ethacrynic acid and corticosteroids both increase potassium excretion, so combined use can cause additive hypokalemia. This matters most with systemically available budesonide, high diuretic doses, or concurrent digoxin or QT-prolonging drugs.
How serious is the interaction between Budesonide and Ethacrynic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium regularly and replace deficits. Adjust the diuretic or add potassium supplementation if hypokalemia develops.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
