Drug interactions
Budesonide + Fluvoxamine
Severity: Minor
Budesonide and Fluvoxamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluvoxamine inhibits CYP3A4 to a modest degree and may increase budesonide exposure. Clinically significant corticosteroid excess is possible mainly with oral budesonide or long-term use.
What this interaction means in plain words
Budesonide and Fluvoxamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Fluvoxamine belongs to Central Nervous System.
Why it happens
Inhibition of CYP3A4 by fluvoxamine may reduce budesonide metabolism.
What to do
Monitor for signs of corticosteroid excess such as Cushingoid features if used long term; no routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Fluvoxamine
- Agomelatine + Fluvoxamine Contraindicated
- Alosetron + Fluvoxamine Contraindicated
- Fezolinetant + Fluvoxamine Contraindicated
- Fluvoxamine + Isocarboxazid Contraindicated
- Fluvoxamine + Mavacamten Contraindicated
- Fluvoxamine + Methylene blue Contraindicated
Frequently asked questions
Can I take Budesonide with Fluvoxamine?
MediHelp rates the interaction as minor. Budesonide and Fluvoxamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluvoxamine inhibits CYP3A4 to a modest degree and may increase budesonide exposure. Clinically significant corticosteroid excess is possible mainly with oral budesonide or long-term use.
How serious is the interaction between Budesonide and Fluvoxamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of corticosteroid excess such as Cushingoid features if used long term; no routine dose change is needed.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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