Drug interactions
Budesonide + Lasmiditan
Severity: Minor
Budesonide and Lasmiditan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan inhibits P-glycoprotein in the intestine, which could modestly raise exposure of P-gp substrates. Budesonide is a minor P-gp substrate and its clearance is dominated by CYP3A4, so a clinically meaningful effect is unlikely.
What this interaction means in plain words
Budesonide and Lasmiditan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Lasmiditan belongs to Central Nervous System.
Why it happens
Lasmiditan inhibits intestinal P-glycoprotein efflux, potentially increasing budesonide absorption.
What to do
No routine adjustment is needed; watch for corticosteroid adverse effects if high-dose or prolonged budesonide is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Budesonide and Lasmiditan, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Budesonide
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Budesonide with Lasmiditan?
MediHelp rates the interaction as minor. Budesonide and Lasmiditan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lasmiditan inhibits P-glycoprotein in the intestine, which could modestly raise exposure of P-gp substrates. Budesonide is a minor P-gp substrate and its clearance is dominated by CYP3A4, so a clinically meaningful effect is unlikely.
How serious is the interaction between Budesonide and Lasmiditan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; watch for corticosteroid adverse effects if high-dose or prolonged budesonide is used.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
