Drug interactions
Budesonide + Magnesium oxide
Severity: Minor
Budesonide and Magnesium oxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium oxide raises gastric pH, which may cause pH-dependent oral budesonide formulations to release the drug prematurely. Absorption and local intestinal effect could change.
What this interaction means in plain words
Budesonide and Magnesium oxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Magnesium oxide belongs to Gastrointestinal Tract.
Why it happens
Increased gastric pH disrupts the pH-dependent coating or release of enteric-coated and extended-release budesonide.
What to do
Separate magnesium oxide from oral budesonide by at least 2 hours. Monitor disease control.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Magnesium oxide
- Chloroquine + Magnesium oxide Moderate
- Ciprofloxacin + Magnesium oxide Moderate
- Dolutegravir + Magnesium oxide Moderate
- Doxycycline + Magnesium oxide Moderate
- Eltrombopag + Magnesium oxide Moderate
- Gemifloxacin + Magnesium oxide Moderate
Frequently asked questions
Can I take Budesonide with Magnesium oxide?
MediHelp rates the interaction as minor. Budesonide and Magnesium oxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Magnesium oxide raises gastric pH, which may cause pH-dependent oral budesonide formulations to release the drug prematurely. Absorption and local intestinal effect could change.
How serious is the interaction between Budesonide and Magnesium oxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate magnesium oxide from oral budesonide by at least 2 hours. Monitor disease control.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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