Drug interactions
Budesonide + Nisoldipine
Severity: Minor
Budesonide and Nisoldipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Budesonide is a weak CYP3A4 inducer in theory, and nisoldipine is a CYP3A4 substrate with high first-pass metabolism. Any reduction in nisoldipine exposure is likely small and of limited clinical significance.
What this interaction means in plain words
Budesonide and Nisoldipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Nisoldipine belongs to Cardiovascular.
Why it happens
Possible mild CYP3A4 induction by budesonide could increase nisoldipine metabolism; the effect is not well established.
What to do
No routine adjustment is needed; check blood pressure response if control appears to change.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Nisoldipine
- Itraconazole + Nisoldipine Contraindicated
- Ketoconazole + Nisoldipine Contraindicated
- Apalutamide + Nisoldipine Major
- Carbamazepine + Nisoldipine Major
- Chloramphenicol + Nisoldipine Major
- Clarithromycin + Nisoldipine Major
Frequently asked questions
Can I take Budesonide with Nisoldipine?
MediHelp rates the interaction as minor. Budesonide and Nisoldipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Budesonide is a weak CYP3A4 inducer in theory, and nisoldipine is a CYP3A4 substrate with high first-pass metabolism. Any reduction in nisoldipine exposure is likely small and of limited clinical significance.
How serious is the interaction between Budesonide and Nisoldipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; check blood pressure response if control appears to change.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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