Drug interactions
Budesonide + Oxaliplatin
Severity: Moderate
Budesonide and Oxaliplatin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxaliplatin causes myelosuppression and immune compromise, and corticosteroids add immunosuppression, which may increase the risk of infection. The effect is dependent on budesonide's systemic exposure, which is low for inhaled or locally acting forms.
What this interaction means in plain words
Budesonide and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide belongs to Respiratory; Oxaliplatin belongs to Oncology.
Why it happens
Additive immunosuppression from chemotherapy-induced myelosuppression and corticosteroid effects on immune function.
What to do
Monitor blood counts and for signs of infection during chemotherapy. Use the lowest effective budesonide dose and treat infections promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Budesonide and Oxaliplatin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Budesonide
Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Frequently asked questions
Can I take Budesonide with Oxaliplatin?
MediHelp rates the interaction as moderate. Budesonide and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxaliplatin causes myelosuppression and immune compromise, and corticosteroids add immunosuppression, which may increase the risk of infection. The effect is dependent on budesonide's systemic exposure, which is low for inhaled or locally acting forms.
How serious is the interaction between Budesonide and Oxaliplatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and for signs of infection during chemotherapy. Use the lowest effective budesonide dose and treat infections promptly.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
