Drug interactions
Budesonide + Rosiglitazone
Severity: Minor
Budesonide and Rosiglitazone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Budesonide can raise blood glucose and blunt the effect of rosiglitazone. Both can cause fluid retention, which is relevant in patients with heart failure risk.
What this interaction means in plain words
Budesonide and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Rosiglitazone belongs to Endocrine.
Why it happens
Pharmacodynamic antagonism from corticosteroid-induced insulin resistance, plus additive fluid retention.
What to do
Monitor blood glucose and signs of fluid retention, and adjust antidiabetic therapy if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Major
- Insulin aspart-insulin aspart protamine + Rosiglitazone Major
- Insulin aspart + Rosiglitazone Major
- Insulin degludec / insulin aspart + Rosiglitazone Major
- Insulin degludec-insulin aspart + Rosiglitazone Major
- Insulin degludec-liraglutide + Rosiglitazone Major
Frequently asked questions
Can I take Budesonide with Rosiglitazone?
MediHelp rates the interaction as minor. Budesonide and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Budesonide can raise blood glucose and blunt the effect of rosiglitazone. Both can cause fluid retention, which is relevant in patients with heart failure risk.
How serious is the interaction between Budesonide and Rosiglitazone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and signs of fluid retention, and adjust antidiabetic therapy if control worsens.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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