Drug interactions
Budesonide-formoterol + Deflazacort
Severity: Moderate
Budesonide-formoterol and Deflazacort: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both formoterol and systemic corticosteroids such as deflazacort can lower serum potassium, and the effects may add together. Significant hypokalemia can predispose to cardiac arrhythmias, particularly in patients with cardiac disease or hypoxia.
What this interaction means in plain words
Budesonide-formoterol and Deflazacort can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Deflazacort belongs to Miscellaneous.
Why it happens
Additive hypokalemia from beta-2 agonist-induced intracellular potassium shift and corticosteroid mineralocorticoid-related renal potassium loss.
What to do
Monitor serum potassium in patients on regular or high-dose formoterol with deflazacort, especially during acute illness. Supplement potassium if levels fall.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Budesonide-formoterol and Deflazacort, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Budesonide-formoterol
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Deflazacort?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Deflazacort can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both formoterol and systemic corticosteroids such as deflazacort can lower serum potassium, and the effects may add together. Significant hypokalemia can predispose to cardiac arrhythmias, particularly in patients with cardiac disease or hypoxia.
How serious is the interaction between Budesonide-formoterol and Deflazacort?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients on regular or high-dose formoterol with deflazacort, especially during acute illness. Supplement potassium if levels fall.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
