Drug interactions
Budesonide-formoterol + Fingolimod
Severity: Moderate
Budesonide-formoterol and Fingolimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fingolimod can cause bradycardia and QT prolongation, and formoterol may add to QT effects and tachyarrhythmia risk. The combination may increase the chance of arrhythmia, especially around fingolimod initiation.
What this interaction means in plain words
Budesonide-formoterol and Fingolimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Fingolimod belongs to Central Nervous System.
Why it happens
Additive pharmacodynamic effects on cardiac repolarization and heart rhythm.
What to do
Monitor ECG and heart rate, particularly during the first dose of fingolimod. Correct potassium and magnesium abnormalities in at-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Fingolimod?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Fingolimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fingolimod can cause bradycardia and QT prolongation, and formoterol may add to QT effects and tachyarrhythmia risk. The combination may increase the chance of arrhythmia, especially around fingolimod initiation.
How serious is the interaction between Budesonide-formoterol and Fingolimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and heart rate, particularly during the first dose of fingolimod. Correct potassium and magnesium abnormalities in at-risk patients.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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