Drug interactions
Budesonide-formoterol + Ivosidenib
Severity: Moderate
Budesonide-formoterol and Ivosidenib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ivosidenib prolongs the QT interval in a dose-related way, and formoterol may add to this and lower potassium. The combination increases risk of ventricular arrhythmia.
What this interaction means in plain words
Budesonide-formoterol and Ivosidenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Ivosidenib belongs to Oncology.
Why it happens
Additive QTc prolongation, with beta-agonist induced hypokalemia.
What to do
Monitor ECG and electrolytes at baseline and regularly, correcting potassium and magnesium. Reduce or hold ivosidenib per labeling if QTc rises markedly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Ivosidenib
- Alfuzosin + Ivosidenib Major
- Amiodarone + Ivosidenib Major
- Amisulpride + Ivosidenib Major
- Amitriptyline + Ivosidenib Major
- Amobarbital + Ivosidenib Major
- Anagrelide + Ivosidenib Major
Frequently asked questions
Can I take Budesonide-formoterol with Ivosidenib?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Ivosidenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ivosidenib prolongs the QT interval in a dose-related way, and formoterol may add to this and lower potassium. The combination increases risk of ventricular arrhythmia.
How serious is the interaction between Budesonide-formoterol and Ivosidenib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes at baseline and regularly, correcting potassium and magnesium. Reduce or hold ivosidenib per labeling if QTc rises markedly.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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