Drug interactions
Budesonide-formoterol + Pitolisant
Severity: Moderate
Budesonide-formoterol and Pitolisant: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pitolisant can modestly prolong the QT interval, and formoterol may add to the effect. Risk is greater with electrolyte disturbances or other risk factors.
What this interaction means in plain words
Budesonide-formoterol and Pitolisant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Pitolisant belongs to Central Nervous System.
Why it happens
Additive QTc prolongation, with beta-agonist induced hypokalemia.
What to do
Monitor ECG and electrolytes in patients with cardiac risk factors. Avoid in patients with known QT prolongation.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Pitolisant
- Alfuzosin + Pitolisant Major
- Amiodarone + Pitolisant Major
- Amisulpride + Pitolisant Major
- Anagrelide + Pitolisant Major
- Asenapine + Pitolisant Major
- Bupropion + Pitolisant Major
Frequently asked questions
Can I take Budesonide-formoterol with Pitolisant?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Pitolisant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pitolisant can modestly prolong the QT interval, and formoterol may add to the effect. Risk is greater with electrolyte disturbances or other risk factors.
How serious is the interaction between Budesonide-formoterol and Pitolisant?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes in patients with cardiac risk factors. Avoid in patients with known QT prolongation.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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