Drug interactions
Budesonide-formoterol + Quinine
Severity: Moderate
Budesonide-formoterol and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinine is a known QT-prolonging agent that has caused torsades de pointes. Formoterol may add to QT prolongation and lower potassium, which raises arrhythmia risk.
What this interaction means in plain words
Budesonide-formoterol and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Quinine belongs to Anti Parasitic.
Why it happens
Additive QT prolongation, with beta-2 agonist-induced hypokalemia as a contributing factor.
What to do
Monitor ECG and serum potassium and magnesium, particularly with high formoterol doses or cardiac risk factors. Correct electrolyte deficits.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Quinine?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quinine is a known QT-prolonging agent that has caused torsades de pointes. Formoterol may add to QT prolongation and lower potassium, which raises arrhythmia risk.
How serious is the interaction between Budesonide-formoterol and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium and magnesium, particularly with high formoterol doses or cardiac risk factors. Correct electrolyte deficits.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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